UW Clinical Trials Institute

06 Nov New study shows mRNA vaccine harnesses T-cell power to combat COVID-19 in lungs

Posted at 13:00h in UW–Madison, Wisconsin, Public health, Clinical Trials, COVID-19, Clinical Research

The effectiveness of mRNA vaccines in reducing disease severity and hospitalization from COVID-19 is well established. Now, new research from the University of Wisconsin School of Veterinary Medicine advances our understanding of how these vaccines protect the lungs following breakthrough infections from emerging variants of...

03 Nov UW Study Examines Potential Treatment for Alzheimer’s Disease

Posted at 13:17h in Clinical Trials, Clinical Research, UW Health, UW CTI

Researchers at the University of Wisconsin School of Medicine and Public Health are investigating whether the drug leuprolide, which is approved for prostate cancer in men, can be used to treat symptoms of Alzheimer’s disease in women....

02 Nov Epic and Microsoft partner up

Posted at 13:08h in Clinical Research, UW–Madison, Technology, Wisconsin, Clinical Trials

John Neis, a longtime Madison tech investor, is only a bit more measured as he explains that Epic and Microsoft are focused on one of the biggest challenges in healthcare: “the inordinate amount of time consumed documenting physician-patient interactions.”...

31 Oct A landmark gene-editing treatment for sickle cell disease moves closer to reality

Posted at 12:34h in Clinical Trials, Clinical Research, Public health, FDA

The Food and Drug Administration may soon approve a therapy that uses the gene-editing technique called CRISPR to treat sickle cell disease. It would mark the first time gene editing moves from the lab into clinical use....

30 Oct Researchers test high-tech wristband with potential to detect heart attack in minutes

Posted at 10:07h in Clinical Trials, Clinical Research, UW–Madison, UW SMPH

Researchers at the BerbeeWalsh Department of Emergency Medicine in the University of Wisconsin School of Medicine and Public Health are contributing to a national, multicenter trial evaluating a wearable device that may reduce the time it takes to detect a heart attack to just minutes...

28 Oct What If Trial Participants Knew Their Contributions Were for Naught?

Posted at 11:26h in Clinical Trials, Clinical Research, Public health

Clinical trials are the cornerstone of evidence-based medicine. All trial results -- positive, negative, and neutral -- must be made publicly available to allow for transparent decision-making by patients, physicians, and regulators. Without complete data, the evidence gets distorted: harms are downplayed, and benefits are...

24 Oct Phase 3 Trial Begins for Combination Influenza and COVID-19 Vaccine

Posted at 16:29h in Clinical Trials, COVID-19, Clinical Research

Investigators have dosed the first participant in a phase 3 trial for mRNA-1083 (Moderna), a combination vaccine candidate that provides protection against influenza and COVID-19. Investigators anticipate enrolling approximately 8000 individuals in the Northern Hemisphere for the trial, according to a Moderna press release....

Healthcare provider, holding a stethoscope, works on a touchscreen computer.

24 Oct Precision medicine: Promising future as AI, biomarkers and technology bolster the field

Posted at 15:33h in Clinical Trials, Clinical Research, Technology

Technology is having a significant impact in healthcare and its impact in the development of precision medicine is set to be huge....

24 Oct Bringing Patients into the Trial Results-Sharing Loop is a ‘Win for Everyone Involved’

Posted at 12:58h in Clinical Research, Communication, Clinical Trials

While feedback from clinical trial participants that they would like their personal study data and overall trial results to be shared with them has been loud and clear for many years now, effective follow-through from sponsors and sites on such sentiments has historically been more...

23 Oct Wisconsin designated as Regional Tech Hub for biohealth – with UW–Madison helping lead the way

Posted at 14:16h in Clinical Trials, Clinical Research, UW–Madison, UW Health, Technology, Biohealth, Wisconsin

With today’s announcement that Wisconsin has received a Regional Technology and Innovation Hub (Tech Hub) designation focused on biohealth, the University of Wisconsin–Madison expands its national leadership as a collaborative powerhouse in personalized medicine, bioscience and technology...

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