16 Jun Ethical Violations in Clinical Research: Lessons from the Past, Challenges for the Future

By Scott W. Ward, ACRP

This article explores the evolution of ethical standards in clinical research, emphasizing historical violations and contemporary challenges. With a focus on maintaining participant safety, autonomy, and trust, the article provides clinical research professionals with insights into the foundational principles of ethical conduct, regulatory frameworks, and strategies for safeguarding human subjects in modern research environments.

Background

Ethical conduct in clinical research is essential to ensure the rights, safety, and well-being of participants. While ethical standards have evolved significantly, past violations have left lasting scars, and new challenges continue to emerge. Clinical research professionals play a crucial role in upholding these standards amidst technological advancements and global expansion of trials. This article examines key ethical violations—both historical and contemporary—alongside the ethical frameworks and oversight mechanisms that guide research practices today. Read more…